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Title: Breast cancer in Egypt: a review of disease presentation and detection strategies
Authors: Omar, S.
Khaled, H.
Gaafar, R.
Zekry, A.R.
Eissa, S.
El Khatib, O.
Issue Date: 2003
Language: English
Abstract: Carcinoma of the breast is the most prevalent cancer among Egyptian women and constitutes 29% of National Cancer Institute cases. Median age at diagnosis is one decade younger than in countries of Europe and North America and most patients are premenopausal. Tumours are relatively advanced at presentation. The majority of tumours are invasive duct subtype and the profile of hormone receptors is positive for estrogen receptors and /or progesterone receptors in less than half of cases. This overview examines genetic changes, potential and established predictive and prognostic markers and end results of surgery, radiotherapy and systemic therapy for early, locally advanced and metastatic disease stages. Disease presentations common to the region and early detection strategies are presented
Description: 448-463
Keywords: Age Distribution
Combined Modality Therapy
DNA-Binding Proteins
Genes, erbB-2
Genetic Predisposition to Disease
Lymphatic Metastasis
Mass Screening
Predictive Value of Tests
Premenopause
Subject: Breast Neoplasms
URI: http://www.who.int/iris/handle/10665/119297
ISSN: 1020-3397
Other Identifiers: http://applications.emro.who.int/emhj/0903/emhj_2003_9_3_448_463.pdf
Appears in Collections:EMRO Journal Articles (EMHJ)



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