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Title: Prevalence of human papillomavirus in Mazandaran Province, Islamic Republic of Iran
Authors: Hamkar, R.
Azad, T. Mokhtari
Mahmoodi, M.
Seyedirashti, S.
Severini, A.
Nategh, R.
Issue Date: 2002
Language: English
Abstract: We report the prevalence of human papillomavirus [HPV] types in 100 cervical biopsy specimens in Mazandaran province. HPV DNA was detected in 78.6% of cervical carcinoma cases, 64.3% of dys/ metaplasia and 9% of normal cases. Significant correlation was found between the presence of HPV DNA and development of cervical carcinoma. HPV types 16 and 18 were detected in 60.6% of HPV-positive cervical carcinoma cases, whereas HPV31 and 33 were found in 21.2%, and HPV6 and 11 in 18.2%. Among HPV-positive dys/metaplasia cases, 55.6% were positive for HPV16 and 18, 22.3% for HPV6 and 11, and 11.1% for HPV31 and 33. Only HPV6 and 11 were detected in 4 [100%] normal biopsy specimens
Description: 805-811
Keywords: Biopsy
Case-Control Studies
Cocarcinogenesis
DNA, Viral
Epidemiology, Molecular
Genotype
In Situ Hybridization
Papillomaviridae
Uterine Cervical Dysplasia
Uterine Cervical Neoplasms
Subject: Papillomavirus Infections
URI: http://www.who.int/iris/handle/10665/119231
ISSN: 1020-3397
Other Identifiers: http://applications.emro.who.int/emhj/0806/emhj_2002_8_6_805_811.pdf
Appears in Collections:EMRO Journal Articles (EMHJ)



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