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Title: Reduction of clinical tuberculosis in HIV-infected males with isoniazid prophylaxis
Authors: Alaei, K.
Alaei, A.
Mansouri, D.
Issue Date: 2002
Language: English
Abstract: Isoniazid [INH] chemoprophylaxis has a positive impact on the development of clinical tuberculosis. Due to the increased prevalence of tuberculosis among HIV-infected individuals, we evaluated the effect of INH on the prevention of clinical tuberculosis in HIV-infected patients. We administered 300 mg of INH daily to 246 HIV-infected, tuberculin skin test-positive patients for 12 months. During 3 years of follow-up, 41 participants died and 94 were lost to follow up. Of the 111 patients followed for the 3 years, 12 developed tuberculosis which is lower than might be expected in an untreated group. INH prophylaxis appears to be an effective method to prevent clinical tuberculosis among HIV-infected, tuberculin skin test-positive patients
Description: 754-757
Keywords: AIDS-Related Opportunistic
Antitubercular Agents
Prospective Studies
Skin Tests
Substance Abuse, Intravenous
Subject: Isoniazid
ISSN: 1020-3397
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Appears in Collections:EMRO Journal Articles (EMHJ)

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