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Title: Vaginal misoprostol in managing premature rupture of membranes
Authors: Ayad, I.A.A.
Issue Date: 2002
Language: English
Abstract: We compared the efficacy of misoprostol with that of prostaglandin E2 in cervical ripening and labour induction. Thus 238 women with rupture of membranes beyond 36 weeks gestation without labour were randomized to receive 50 microg misoprostol vaginal gel or 5 mg of prostaglandin E2 gel. Bishop score was evaluated before drug application and 6 hours later. Clinical data and perinatal outcome were recorded. Mean time from induction to delivery and the need for oxytocin were significantly less in the misoprostol group. There were no significant differences in spontaneous labour rate, type of delivery and perinatal outcome. It is concluded that intravaginal misoprostol is safe and more effective than prostaglandin E2 for preinduction cervical ripening in premature rupture of membranes beyond 36 weeks gestation
Description: 515-520
Keywords: Administration, Intravaginal
Cervical Ripening
Delivery, Obstetric
Fetal Distress
Labor, Induced
Vaginal Creams, Foams, and Jellies
Subject: Fetal Membranes, Premature Rupture
ISSN: 1020-3397
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Appears in Collections:EMRO Journal Articles (EMHJ)

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