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Title: Effect of leptin on LH and FSH release in ovariectomized rats
Authors: Shebl, M.M.
Issue Date: 2002
Language: English
Abstract: We compared the estradiol/progesterone-induced luteinizing hormone [LH] and follicle-stimulating hormone [FSH] release between normally fed and leptin-supplemented starved ovariectomized female rats and studied also the effect of hyper-leptinaemia on the steroid-induced hormonal release in normally fed ovariectomized rats. Three days' starvation completely abolished steroid-induced LH and FSH release. Significant recovery of the hormonal release was shown in the leptin-supplemented starved group. The magnitudes of LH and FSH release in the normally fed animals with a higher dose of leptin were statistically the same as those in the normally fed group without leptin. These observations indicate that physiological concentrations of circulating leptin exert a stimulatory effect on steroid-induced LH and FSH release
Description: 105-113
Keywords: Analysis of Variance
Disease Models, Animal
Follicle Stimulating Hormone
Hypothalamo-Hypophyseal System
Luteinizing Hormone
Neuropeptide Y
Subject: Leptin
ISSN: 1020-3397
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Appears in Collections:EMRO Journal Articles (EMHJ)

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