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Title: Biochemical effects of vinyl chloride monomer on the liver of occupationally exposed workers
Authors: Saad, A.A.
Issue Date: 2000
Language: English
Abstract: We investigated the effects of vinyl chloride monomer exposure on the liver of 86 workers by measuring beta-glucuronidase, arylsulfatase A, adenosine deaminase, 5'-nucleotidase and routine liver function enzymes in the sera of the workers. In 21 of them, three or more of these parameters were raised, with a significant decrease in the level of blood glutathione and a significant increase in the enzyme activity level of glutathione S-transferase. Of these 21 workers, 14 had fatty liver infiltration, 8 of whom were also suffering from liver enlargement. Also, 4 workers had liver enlargement without fatty infiltration and 3 had enlarged spleens. The study highlights the need for vigilance in environmental monitoring and medical surveillance of workers exposed to this chemical
Description: 979-986
Keywords: Occupational Exposure
Subject: Vinyl Chloride
ISSN: 1020-3397
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Appears in Collections:EMRO Journal Articles (EMHJ)

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