Files in This Item:
   
ThumbnailEMHJ_2000_6_5-6_888_897.pdf

View/Open

Title: Comparision between Toxoplasma gondii DNA and specific immunoglobulins during pregnancy
Authors: El Awady, M.K.
Issue Date: 2000
Language: English
Abstract: Early diagnosis of toxoplasmosis in pregnant women can be of great help in early intervention and prevention of congenital disorders that usually lead to fetal death. The purpose of the present study was to evaluate nested PCR amplification of the B1 gene of Toxoplasma gondii before and after treatment and in comparison to serological follow-up during treatment. The efficiency of treatment on the bases of PCR detection of T. gondii DNA was statistically significant, while it was insignificant when anti-toxoplasma specific IgM and IgG antibodies were used. PCR detection of T. gondii DNA when performed on whole blood is a rapid, sensitive and specific diagnostic procedure and is a valuable tool for establishing the diagnosis of T. gondii infection in women before or during pregnancy
Description: 888-897
Keywords: Polymerase Chain Reaction
Immunoglobulins
Immunoglobulin M
Immunoglobulin G
Toxoplasma
DNA, Protozoon
Pregnancy
Subject: Toxoplasmosis
URI: http://www.who.int/iris/handle/10665/118943
ISSN: 1020-3397
Other Identifiers: http://applications.emro.who.int/emhj/0605_6/EMHJ_2000_6_5-6_888_897.pdf
Appears in Collections:EMRO Journal Articles (EMHJ)



Items in WHO IRIS are protected by copyright, with all rights reserved, unless otherwise indicated.