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dc.contributor.authorEl Hazmi, M.A.
dc.contributor.authorWarsy, A.S.
dc.contributor.authorBashir, N.
dc.contributor.authorBeshlawi, A.
dc.contributor.authorHussain, I.R.
dc.contributor.authorTemtamy, S.
dc.contributor.authorQubaili, F.
dc.date.accessioned2014-06-17T10:42:18Z
dc.date.available2014-06-17T10:42:18Z
dc.date.issued1999EN
dc.identifier.issn1020-3397EN
dc.identifier.otherhttp://applications.emro.who.int/emhj/0506/EMHJ_1999_5_6_1154_1158.pdfEN
dc.identifier.urihttps://iris.who.int/handle/10665/118810
dc.description1154-1158EN
dc.description.abstractWe collaborated with researchers from Egypt, Syrian Arab Republic and Jordan in a study of patients with sickle-cell disease from those countries, and from various parts of Saudi Arabia, in order to investigate the influence of genetics on the clinical presentation of the disease, and to attempt to determine the origin of the sickle-cell gene in Arabs. Our results suggest that beta-globin gene haplotypes influence the clinical presentation of sickle-cell disease, and that there are at least two major foci for the origin of the sickle-cell gene, one in the eastern part of Saudi Arabia, and the other in the populations of North Africa and the north-western part of the Arabian peninsulaEN
dc.language.isoenEN
dc.subjectGenetic ScreeningEN
dc.subjectGlobinsEN
dc.subjectHaplotypesEN
dc.subjectPolymorphism, GeneticEN
dc.subjectPrognosisEN
dc.subjectResidence CharacteristicsEN
dc.subjectSeverity of Illness IndexEN
dc.subjectVariation [‎Genetics]‎EN
dc.subject.meshAnemia, Sickle CellEN
dc.titleHaplotypes of the beta-globin gene as prognostic factors in sickle-cell diseaseEN
dc.relation.ispartofjournalEMHJ - Eastern Mediterranean Health Journal, 5 (‎6)‎, 1154-1158, 1999


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