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Title: Triclabendazole in the treatment of human fascioliasis: a community-based study
Authors: El Morshedy, H.
Farghaly, A.
Sharaf, S.
Abou Basha, L.
Barakat, R.
Issue Date: 1999
Language: English
Abstract: The efficacy of triclabendazole in the treatment of chronic Fasciola infection was assessed. A total of 134 asymptomatic cases of established Fasciola infection were treated: 68 individuals received a single dose of 10 mg/kg and 66 individuals received 2 doses of 10 mg/kg on 2 consecutive days. Cure was assessed 5 weeks after treatment and 79.4% of the first group and 93.9% of the second group were cured. The drug was well tolerated; no serious side-effects were noted. One patient developed biochemical cholestasis the third day after treatment, but her enzyme profiles returned to normal after 2 months. We conclude triclabendazole is a safe and potent fasciolicidic drug
Description: 888-894
Keywords: Anthelmintics
Child, Preschool
Chronic Disease
Drug Administration Schedule
Endemic Diseases
Liver Function Tests
Treatment Outcome
Subject: Fascioliasis
ISSN: 1020-3397
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Appears in Collections:EMRO Journal Articles (EMHJ)

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