|Title:||Triclabendazole in the treatment of human fascioliasis: a community-based study|
|Authors:||El Morshedy, H.|
Abou Basha, L.
|Abstract:||The efficacy of triclabendazole in the treatment of chronic Fasciola infection was assessed. A total of 134 asymptomatic cases of established Fasciola infection were treated: 68 individuals received a single dose of 10 mg/kg and 66 individuals received 2 doses of 10 mg/kg on 2 consecutive days. Cure was assessed 5 weeks after treatment and 79.4% of the first group and 93.9% of the second group were cured. The drug was well tolerated; no serious side-effects were noted. One patient developed biochemical cholestasis the third day after treatment, but her enzyme profiles returned to normal after 2 months. We conclude triclabendazole is a safe and potent fasciolicidic drug|
Drug Administration Schedule
Liver Function Tests
|Appears in Collections:||EMRO Journal Articles (EMHJ)|
Items in WHO IRIS are protected by copyright, with all rights reserved, unless otherwise indicated.