Files in This Item:


Title: Immunohistochemical detection of p53 protein in ameloblastoma types
Authors: El Sissy, N.A.
Issue Date: 1999
Language: English
Abstract: Overexpression of p53 protein in unicystic ameloblastoma [uAB] is denser than in the conventional ameloblastoma [cAB] type, indicating increased wild type p53 - suppressing the growth potential of uAB and denoting the early event of neoplastic transformation, probably of a previous odontogenic cyst. Overexpression of p53 in borderline cAB and malignant ameloblastoma [mAB] types might reflect a mutational p53 protein playing an oncogenic role, promoting tumour growth. Overexpression of p53 protein could be a valid screening method for predicting underlying malignant genetic changes in AB types, through increased frequency of immunoreactive cells or increased staining density
Description: 478-489
Keywords: Immunohistochemistry
Mandibular Neoplasms
Maxillary Neoplasms
Subject: Ameloblastoma
ISSN: 1020-3397
Other Identifiers:
Appears in Collections:EMRO Journal Articles (EMHJ)

Items in WHO IRIS are protected by copyright, with all rights reserved, unless otherwise indicated.