Acute graft-versus-host disease in thalassaemic marrow transplantation with low-dose antithymocyte globulin
AbstractOur unit performed transplantations on 21 classes II and III thalassaemic patients [class II patients had either hepatomegaly or portal fibrosis and class III patients had both]. We used busulfan [15 mg/kg] and cyclophosphamide [200 mg/kg]. Graft-versus-host disease [GVHD] prophylaxis was cyclosporin, prednisolone and low-dose antithymocyte globulin. Our patient data showed a low incidence of acute GVHD following transplantation. We offer this regimen as an acceptable therapy for thalassaemic patients undergoing allogeneic marrow transplantation as a safe clinical procedure, irrespective of the class of patient
Khojasteh, H.N. (1999). Acute graft-versus-host disease in thalassaemic marrow transplantation with low-dose antithymocyte globulin. http://www.who.int/iris/handle/10665/118728
EMHJ - Eastern Mediterranean Health Journal, 5 (3), 465-469, 1999
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