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Title: Acute graft-versus-host disease in thalassaemic marrow transplantation with low-dose antithymocyte globulin
Authors: Khojasteh, H.N.
Issue Date: 1999
Language: English
Abstract: Our unit performed transplantations on 21 classes II and III thalassaemic patients [class II patients had either hepatomegaly or portal fibrosis and class III patients had both]. We used busulfan [15 mg/kg] and cyclophosphamide [200 mg/kg]. Graft-versus-host disease [GVHD] prophylaxis was cyclosporin, prednisolone and low-dose antithymocyte globulin. Our patient data showed a low incidence of acute GVHD following transplantation. We offer this regimen as an acceptable therapy for thalassaemic patients undergoing allogeneic marrow transplantation as a safe clinical procedure, irrespective of the class of patient
Description: 465-469
Keywords: Graft Vs Host Disease
Thalassemia
Bone Marrow Transplantation
Acute Disease
Transplantation, Homologous
Cyclosporins
Prednisolone
Subject: Graft vs Host Disease
URI: http://www.who.int/iris/handle/10665/118728
ISSN: 1020-3397
Other Identifiers: http://applications.emro.who.int/emhj/0503/EMHJ_1999_5_3_465_469.pdf
Appears in Collections:EMRO Journal Articles (EMHJ)



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