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Title: Prevalence of coeliac disease among adult patients with autoimmune hypothyroidism in Jordan
Authors: Farahid, O.H.
Khawaja, N.
Shennak, M.M.
Batieha, A.
El Khateeb, M.
Ajlouni , K.
Issue Date: 2014
Language: English
Abstract: The prevalence of coeliac disease among patients with autoimmune hypothyroidism has not been studied before in Jordan and other Arab countries. A cross-sectional record-based review was made of all adult autoimmune hypothyroidism patients who attended a referral centre in Jordan, during an 8-month period. Coeliac disease in these patients was diagnosed by the attending physician based on positive serological tests for anti-endomysial antibodies IgA and IgG followed by duodenal biopsy to confirm the diagnosis of coeliac disease. Of 914 patients recruited, 117 [12.8%] were seropositive for coeliac disease. Of 87 seropositive patients who underwent duodenal biopsy, 39 had positive histological findings of coeliac disease [44.8%]. Extrapolating from these findings the overall rate of coeliac disease among autoimmune hypothyroidism patients was estimated to be 5.7%. In multivariate logistic regression coeliac disease was significantly associated with older age [> 40 years], presence of other autoimmune diseases, vitamin B12 deficiency and anaemia
Description: 51-55
ISSN: 1020-3397
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Appears in Collections:EMRO Journal Articles (EMHJ)

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