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Title: Dual addictions, parallel treatments: nicotine replacement therapy for patients receiving methadone treatment in the Islamic Republic of Iran
Authors: Heydari, G.
Talischi, F.
Batmanghelidj, E.
Pajooh, MR.
Boroomand, A.
Zamani, M.
Salehi, A.
Maddah, S.
Issue Date: 2013
Language: English
Abstract: This parallel, randomized, open-ended clinical trial tested the impact of nicotine replacement pharmacotherapy during the course of methadone treatment among opiate abusers. A total of 424 men entered the study at 4 drug treatment centres in Tehran, Islamic Republic of Iran. The intervention group received a 6-week regimen of nicotine replacement pharmacotherapy at no charge. After 6 months, 211 persons [99.5%] in the control group continued to smoke and 1 person [0.5%] had quit. In the intervention group, 117 [55.1%] persons smoked, 15 [7.1%] persons had quit and 80 [37.7%] had reduced by more than 50% the number of cigarettes they smoked at the start of the study [P < 0.0001]. The findings suggest that the use of nicotine replacement pharmacology in tandem with methadone maintenance treatment can lead to dramatically improved efficacy for treatment of dual addictions
Description: 1-10
URI: http://www.who.int/iris/handle/10665/118597
ISSN: 1020-3397
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Appears in Collections:EMRO Journal Articles (EMHJ)



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