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Title: Serological pattern of hepatitis B virus among HBsAg negative blood donors in Alexandria, Egypt
Authors: El Ghitany, E.M.
Farghaly, A.G.
Issue Date: 2013
Language: English
Abstract: This study in Alexandria, Egypt was conducted to investigate the distribution of different hepatitis B virus [HBV] markers in apparently healthy blood donors who were hepatitis B surface antigen [HBsAg] negative, and to determine the major independent risk factors. Evidence of past exposure to HBV was found in 148/508 screened donors [29.1%]. The most prevalent marker was anti-HBc in 124/508 donors [24.4%], half of whom [63/124] showed anti-HBc only. Anti-HBs prevalence was 15.9%, combined anti-HBc and antiHBs was 12.0% and anti-HBe was 5.7%. Independent risk factors associated with the presence of at least 1 marker were: being married [OR 3.82], history of blood transfusion [OR 3.04] and parenteral antibilharzial treatment [OR 2.49]. Receiving a full HBV vaccination schedule was reported by 39 donors, but only 1 of them had isolated anti-HBs. The relatively high prevalence of HBV exposure necessitates solid infection control measures and adult vaccination programme awareness
Description: 600 - 607
Keywords: Serologic Tests
Hepatitis B Surface Antigens
Blood Donors
Biological Markers
Risk Factors
Hepatitis B Core Antigens
Hepatitis B e Antigens
Subject: Hepatitis B virus
URI: http://www.who.int/iris/handle/10665/118557
ISSN: 1020-3397
Other Identifiers: http://applications.emro.who.int/emhj/v19/07/EMHJ_2013_19_7_600_607.pdf
Appears in Collections:EMRO Journal Articles (EMHJ)



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