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Title: Impact of the mandatory age-based single-embryo transfer legislation in Turkey on outcome of in vitro fertilization:a multicentre study
Authors: Ergun, B.
Bastu, E.
Galandarov, R.
Koksal, G.
Yumru, H.
Attar, E.
Issue Date: 2013
Language: English
Abstract: This study in Turkey evaluated the impact of age-based mandatory single-embryo transfer [SET] legislation with the subsequent increase in frozen-thawed embryo transfer [FT-ET] on pregnancy outcome of in vitrofertilization [IVF] patients. SET, FT-ET and double-embryo transfer were used in 5632 patients after legislation, while traditional IVF and FT-ET approach was used in 6029 patients before legislation. The cumulative pregnancy rate after legislation was slightly lower [38.2%] than before legislation [42.0%] but not significantly so. The single pregnancy rate for SET and traditional IVF were similar between the 2 groups [37.8% versus 28.7%], while multiple pregnancy rates were significantly higher before than after legislation [13.7% versus 0.3%]. For FT-ET, the number of cycles was significantly higher after legislation [862 versus 616]. SET yielded similar results to traditional IVF. In order to reduce multiple pregnancies without significantly decreasing pregnancy rates, SET might be a successful strategy
Description: 733 - 738
Keywords: Pregnancy Outcome
Legislation, Medical
Fertilization in Vitro
Retrospective Studies
Ovulation Induction
Sperm Injections, Intracytoplasmic
Subject: Single Embryo Transfer
ISSN: 1020-3397
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Appears in Collections:EMRO Journal Articles (EMHJ)

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