Impact of the mandatory age-based single-embryo transfer legislation in Turkey on outcome of in vitro fertilization:a multicentre study
AbstractThis study in Turkey evaluated the impact of age-based mandatory single-embryo transfer [SET] legislation with the subsequent increase in frozen-thawed embryo transfer [FT-ET] on pregnancy outcome of in vitrofertilization [IVF] patients. SET, FT-ET and double-embryo transfer were used in 5632 patients after legislation, while traditional IVF and FT-ET approach was used in 6029 patients before legislation. The cumulative pregnancy rate after legislation was slightly lower [38.2%] than before legislation [42.0%] but not significantly so. The single pregnancy rate for SET and traditional IVF were similar between the 2 groups [37.8% versus 28.7%], while multiple pregnancy rates were significantly higher before than after legislation [13.7% versus 0.3%]. For FT-ET, the number of cycles was significantly higher after legislation [862 versus 616]. SET yielded similar results to traditional IVF. In order to reduce multiple pregnancies without significantly decreasing pregnancy rates, SET might be a successful strategy
Ergun, B., Bastu, E., Galandarov, R., Koksal, G., Yumru, H. et al. (2013). Impact of the mandatory age-based single-embryo transfer legislation in Turkey on outcome of in vitro fertilization:a multicentre study. http://www.who.int/iris/handle/10665/118534
EMHJ - Eastern Mediterranean Health Journal, 19 (8), 733 - 738, 2013
Description733 - 738
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Mahani, I.M.; Davar, R. (2007)We compared the implantation and pregnancy rate through in vitro fertilization [IVF] using hyaluronic acid and albumin as transfer medium in 60 women randomly allocated to 2 groups. In treatment group A [n = 30], embryos were transferred to medium supplemented with hyaluronic acid. In the control group B [n = 30], embryos were transferred to medium containing albumin. There were no significant differences between the groups in terms of mean age of the females, mean duration of infertility and mean number of embryos. The pregnancy rate in groups ...
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