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Title: Relation between some haematological abnormalities, degree of immunosuppression and viral load in treatment-na‹ve HIV-infected patients
Authors: Denue, B.A.
Gashau, W.
Bello, H.S.
Kida, I.M.
Bakki, B.
Ajayi, B.
Issue Date: 2013
Language: English
Abstract: This cross-sectional study at a teaching hospital in north-eastern Nigeria estimated the prevalence of anaemia, leukopenia and thrombocytopenia in treatment-naive HIV-infected patients [177 males and 316 females], and the associations with virological and immunological markers. The overall prevalences of anaemia, leukopenia and thrombocytopenia were 49.5%, 5.5% and 4.5% respectively. The prevalence of anaemia was significantly higher in males than females [61.6% versus 42.7%], while the rates of leukopenia [5.1% versus 5.7%] and thrombocytopenia [5.7% versus 3.8%] were similar. Almost two-thirds of the HIV treatment-naive studied patients, 293/493 [59.4%], had cytopenia and would require antiretroviral drugs. AIDS was diagnosed by clinical or immunological criteria in 70% of patients. The degree of cytopenia was directly related to the degree of immunosuppresslon and clinical AIDS status. No relationship was observed between cytopenia and viral load
Description: 362 - 368
Keywords: Hematologic Tests
Immunosuppression
Viral Load
Cross-Sectional Studies
Hospitals, Teaching
Anemia
Leukopenia
Thrombocytopenia
Acquired Immunodeficiency Syndrome
Prospective Studies
Cohort Studies
CD4 Lymphocyte Count
Subject: HIV Infections
URI: http://www.who.int/iris/handle/10665/118395
ISSN: 1020-3397
Other Identifiers: http://applications.emro.who.int/emhj/v19/04/EMHJ_2013_19_4_362_368.pdf
Appears in Collections:EMRO Journal Articles (EMHJ)



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