Relation between some haematological abnormalities, degree of immunosuppression and viral load in treatment-na‹ve HIV-infected patients
AbstractThis cross-sectional study at a teaching hospital in north-eastern Nigeria estimated the prevalence of anaemia, leukopenia and thrombocytopenia in treatment-naive HIV-infected patients [177 males and 316 females], and the associations with virological and immunological markers. The overall prevalences of anaemia, leukopenia and thrombocytopenia were 49.5%, 5.5% and 4.5% respectively. The prevalence of anaemia was significantly higher in males than females [61.6% versus 42.7%], while the rates of leukopenia [5.1% versus 5.7%] and thrombocytopenia [5.7% versus 3.8%] were similar. Almost two-thirds of the HIV treatment-naive studied patients, 293/493 [59.4%], had cytopenia and would require antiretroviral drugs. AIDS was diagnosed by clinical or immunological criteria in 70% of patients. The degree of cytopenia was directly related to the degree of immunosuppresslon and clinical AIDS status. No relationship was observed between cytopenia and viral load
Denue, B.A., Gashau, W., Bello, H.S., Kida, I.M., Bakki, B. et al. (2013). Relation between some haematological abnormalities, degree of immunosuppression and viral load in treatment-na‹ve HIV-infected patients. http://www.who.int/iris/handle/10665/118395
EMHJ - Eastern Mediterranean Health Journal, 19 (4), 362 - 368, 2013
Description362 - 368
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