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Title: Quantitative estimation of interferon-gamma levels among Egyptian polytransfused haematology cases
Authors: Roshdy, M.N.
Harfoush, R.A.
Hamed, N.A.
Morsi, M.G.
Issue Date: 2013
Language: English
Abstract: This study was designed to estimate interferon-gamma [INF-gamma] levels among polytransfused haematology cases. Cases were selected from the haematology unit of Alexandria main university hospital, Egypt. Complete blood counts, estimation of INF-gamma and hepatitis B and C virus [HBV and HCV] status were conducted on 20 unsplenectomized patients with thalassaemia major and 20 patients with acute myeloid leukaemia [AML] in the maintenance phase and 20 healthy subjects. Mean haemoglobin levels and red blood cell counts were significantly higher in the control group than the AML and thalassaemia groups, while white blood cell counts were significantly lower in the control group than the case groups. Two AML patients [10%] and 1 thalassaemia patient [5%] were HBV-positive, while 5% of both case groups were HCV-positive. Mean values of INF-? were significantly different between AML, thalassaemia major and control groups: 5517 [SD 1142] pg/mL, 1024 [SD 249] pg/mL and 2980 [SD 604] pg/mL respectively
Description: 490 - 494
Keywords: Blood Transfusion
Blood Cell Count
Hepatitis B virus
Hepacivirus
beta-Thalassemia
Leukemia, Myeloid, Acute
Hemoglobins
Subject: Interferon-gamma
URI: http://www.who.int/iris/handle/10665/118381
ISSN: 1020-3397
Other Identifiers: http://applications.emro.who.int/emhj/v19/05/EMHJ_2013_19_5_490_494.pdf
Appears in Collections:EMRO Journal Articles (EMHJ)



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