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Title: Etiological profile of pancytopenia in adults in Marrakesh, Morocco
Authors: Nafil, H.
Tazi, I.
Sifsalam, M.
Bouchtia, M.
Mahmal, L.
Issue Date: 2012
Language: English
Abstract: This retrospective study evaluated the frequency of different causes of pancytopenia in all adult patients with pancytopenia presenting to the Department of Haematology of Mohamed VI Hospital, Marrakesh from 1 January 2008 to 31 December 2010. A total of 118 cases of pancytopenia were found [average of 39 cases per year]. The mean age of patients was 52 years [range 18-82 years] and 52.5% were male. The main clinical signs were pallor [100%], asthenia [100%] and fever [30.5%]. Mean haemoglobin was 6.5 g/dL [range 2.9-9.2 g/dL], mean white blood cell count was 2360/mm[3] [range 840-3360/mm[3]] and platelet count 66 000/mm[3] [range 3000-123 000/mm[3]]. Bone marrow aspiration was performed in 112 patients; megaloblastosis was found in 32.2% and marrow blasts in 23.7%. Anaemia due to vitamin B[12] deficiency [32.2%], acute leukaemia [23.7%] and aplastic anaemia [15.2%] were the main causes of pancytopenia. Given the incidence of acute leukemia among our cases, patients presenting with pancytopenia require urgent diagnosis and treatment
Description: 532-536
Keywords: Pancytopenia
Bone Marrow Examination
Anemia, Megaloblastic
Anemia, Aplantic
Subject: Pancytopenia
ISSN: 1020-3397
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Appears in Collections:EMRO Journal Articles (EMHJ)

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