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Title: Epidemiological and biologic profile of breast cancer in Fez-Boulemane, Morocco
Authors: Abbass, F.
Bennis, S.
Znati, K.
Akasbi, Y.
Amrani, J.K.
El Mesbahi, O.
Amarti, M.
Issue Date: 2011
Language: French
Abstract: In a retrospective study of 265 patients with breast cancer over 3 years [January 2007-September 2009] we examined the epidemiological profile of breast cancer to determine the impact of biological and prognostic factors on survival over 3 years and on the epidemiology of this cancer. Estrogen [RE], progesterone [RP] and human epidermal growth factor receptors [HER2] were evaluated and RE/RP/HER2 status determined. The patients were young [median age 45 years]. Invasive tumours were found in 95.5% of the women. The average tumour size was big [3.6 [SD 2.6] cm] and only 14% were histological grade I. Large tumour size and high histological grade were independent of patient's age. Overall survival at 3 years was only 49% for the RE-/RP-/HER2- subtype and 75% for the RE-/RP-/HER2+ subtype, while it was 96% for the RE+/RP+/HER2- subtype. The young age, large tumour size and high histological grade in our population suggest a lack of awareness of women about breast cancer
Description: 930-936
Keywords: Retrospective Studies
Prognosis
Breast Neoplasms
Awareness
Immunohistochemistry
Subject: Breast Neoplasms
URI: http://www.who.int/iris/handle/10665/118224
ISSN: 1020-3397
Other Identifiers: http://applications.emro.who.int/emhj/V17/12/17_12_2011_0930_0936.pdf
Appears in Collections:EMRO Journal Articles (EMHJ)



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