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Title: Viral infections detected by serology and PCR of perilymphatic fluid in children with idiopathic sensorineural hearing loss
Authors: Noorbakhsh, S.
Farhadi, M.
Daneshi, A.
Mohamadi, S.
Tabatabaei, A.
Issue Date: 2011
Language: English
Abstract: The etiology of sensorineural hearing loss [SNHL] in children may be viral. This cross-sectional study aimed to determine the role of viral infectious agents in children with idiopathic SNHL Of 119 children with SNHL aged 3-168 months undergoing cochlear implant surgery at a hospital in Tehran, no cause could be established in 18 cases [15.1%]. Cytomegalovirus [CMV] and herpes simplex virus [HSV] active infections [detected by DNA-PCR, confirmed by serology] were found in the perilymphatic fluid of 16.7% [3/18] cases of idiopathic SNHL Serology was performed on blood samples from 11 of these cases: specific antibodies against CMV, Toxoplasmo spp., HSV and rubella were determined in all cases; acute T. gondii infection was detected in 7 cases and rubella IgG was found in only 1 case. Neonatal screening for CMV, HSV and T. gondii may be helpful in the Islamic Republic of Iran
Description: 867-870
Keywords: Virus Diseases
Virus Diseases
Cross-Sectional Studies
Polymerase Chain Reaction
Cross-Sectional Studies
Questionnaires
Subject: Hearing Loss, Sensorineural
URI: http://www.who.int/iris/handle/10665/118200
ISSN: 1020-3397
Other Identifiers: http://applications.emro.who.int/emhj/V17/11/17_11_2011_0868_0871.pdf
Appears in Collections:EMRO Journal Articles (EMHJ)



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