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Title: Correlation of serum alkaline phosphatase with clinicopathological characteristics of patients with oesophageal cancer
Authors: Aminian, A.
Karimian, F.
Mirsharifi, R.
Alibakhshi, A.
Hasani, S.M.
Dashti, H.
Jahangiri, Y.
Ghaderi, H.
Meysamie, A.
Issue Date: 2011
Language: English
Abstract: Oesophageal cancer is endemic in some regions of the Islamic Republic of Iran and efforts have been made to find factors that play a role in its prognosis. We retrospectively examined the correlation of serum alkaline phosphatase [ALP] levels with several clinicopathological characteristics of 207 cases of oesophageal carcinoma. The mean ALP level in patients with lymph node involvement was significantly higher [141 [SD 77] U/L] than with node negative cancers [116 [SD 63] U/L]. Patients with ALP level > 165 U/L were 3.29 times more likely to have lymph node involvement than patients with ALP level </= 165 U/L. There was no statistically significant correlation between ALP level and sex, age, tumour histological type, site and size of tumour, depth of penetration, distant metastasis, degree of differentiation, presence of lymphatic invasion and presence of simultaneous multiple cancers. Elevated ALP in patients with oesophageal cancer may predict lymph node involvement
Description: 862-866
Keywords: Esophageal Neoplasms
Esophageal Neoplasms
Alkaline Phosphatase
Retrospective Studies
Alkaline Phosphatase
Subject: Esophageal Neoplasms
ISSN: 1020-3397
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Appears in Collections:EMRO Journal Articles (EMHJ)

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