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Title: Vaccine trial against canine visceral leishmaniasis in the Islamic republic of Iran
Authors: Mohebali, M.
Issue Date: 1998
Language: English
Abstract: Sixteen dogs were randomly divided into four groups. Group 1 received autoclaved Leishmania infantum vaccine with BCG. Group 2 received autoclaved L. major vaccine with BCG. Group 3 received BCG alone and Group 4 received normal saline. Dogs received the vaccines intradermally three times each at 30-day intervals. All dogs were tested at 2-month intervals with the leishmanin skin test and anti-Leishmania ELISA. Ninety days after the third dose, each dog received an intraperitoneal challenge of 2.5 X 10[6] infective promastigotes of L. infantum. Necropsy was performed on all dogs to investigate for parasites. All of the dogs in the unvaccinated groups were infected with L. infantum but of the dogs in the vaccinated groups, only one dog was infected
Description: 234-238
Keywords: BCG Vaccine
Vaccination
Subject: Leishmaniasis, Visceral
URI: http://www.who.int/iris/handle/10665/118040
ISSN: 1020-3397
Other Identifiers: http://applications.emro.who.int/emhj/0402/emhj_1998_4_2_234_238.pdf
Appears in Collections:EMRO Journal Articles (EMHJ)



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