|Title:||Characterization of Mycobacterium tuberculosis in Syrian patients by double-repetitive-element polymerase chain reaction|
|Abstract:||The role of previous treatment in the dynamics of tuberculosis transmission has not been adequately investigated. Mycobacterium tuberculosis isolates from previously treated patients [n = 88] from all regions of Syrian Arab Republic were characterized in terms of antibiotic sensitivity and genotyping using double-repetitive-element polymerase chain reaction [DRE-PCR] method for the proximity of the repetitive DNA elements IS6110 [a mobile genetic element] and PGRS. The 88 isolates resulted in 59 different DRE-PCR patterns. Correlations related to age, sex, region, sensitivity and genotype were examined. All regions of the country showed high levels of genotype diversity, suggesting a low level of transmission of M. tuberculosis strains in previously treated patients|
|Keywords:||Polymerase Chain Reaction|
Microbial Sensitivity Tests
|Appears in Collections:||EMRO Journal Articles (EMHJ)|
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