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Title: Characterization of Mycobacterium tuberculosis in Syrian patients by double-repetitive-element polymerase chain reaction
Authors: Rahmo, A.
Hamze, M.
Issue Date: 2010
Language: English
Abstract: The role of previous treatment in the dynamics of tuberculosis transmission has not been adequately investigated. Mycobacterium tuberculosis isolates from previously treated patients [n = 88] from all regions of Syrian Arab Republic were characterized in terms of antibiotic sensitivity and genotyping using double-repetitive-element polymerase chain reaction [DRE-PCR] method for the proximity of the repetitive DNA elements IS6110 [a mobile genetic element] and PGRS. The 88 isolates resulted in 59 different DRE-PCR patterns. Correlations related to age, sex, region, sensitivity and genotype were examined. All regions of the country showed high levels of genotype diversity, suggesting a low level of transmission of M. tuberculosis strains in previously treated patients
Description: 820-830
Keywords: Polymerase Chain Reaction
Mycobacterium tuberculosis
Microbial Sensitivity Tests
Tuberculosis, Multidrug-Resistant
Subject: Mycobacterium tuberculosis
ISSN: 1020-3397
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Appears in Collections:EMRO Journal Articles (EMHJ)

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