Role of periodontitis in hospital-acquired pneumonia
AbstractThis study evaluated the role of periodontal pathogens in 50 hospitalized patients with hospital-acquired pneumonia compared with 30 healthy controls. Specimens of oropharyngeal aspirate, dental plaque, bronchoalveolar lavage and blood cultured 1 or more pathogens in around 80% of patients, predominately Staphylococcus aureus, followed by coagulase-negative staphylococci, Streptococcus pneumoniae and Klebsiella pneumoniae. Antibiotic sensitivity patterns showed concordance of bacterial cultures from dental plaque and oropharyngeal cavity in 13 patients. C-reactive protein [CRP] levels were significantly higher in patients than in controls and there was a significant correlation between serum and salivary CRP levels. Dental plaque biofilm may promote oral and oropharyngeal colonization of respiratory pathogens in hospitalized subjects
El Attar, M.M., Zaghloul, M.Z. & El Menoufy, H.S. (2010). Role of periodontitis in hospital-acquired pneumonia. http://www.who.int/iris/handle/10665/117918
EMHJ - Eastern Mediterranean Health Journal, 16 (5), 563-569, 2010
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