Ambiguous genitalia in neonates: a 4-year prospective study in a localized area
AbstractThis study aimed to determine the possible etiology of ambiguous genitalia in 41 newborn infants at a referral hospital in Hofuf city, Saudi Arabia. In 46,XX karyotype patients [n = 14], congenital adrenal hyperplasia and general malformation disorder were the most common causes of genital ambiguity, while in 46,XY karyotype patients [n = 18], testosterone pathway biosynthetic defect was the most common cause even in conjunction with a generalized malformation disorder. In patients with abnormal karyotype [n = 3], 1 had trisomy 18 [47,XX] and died after 3 months and 2 had different types of mosaic Turner syndrome. The karyotype was undetermined in 6 patients. Positive family history of ambiguous genitalia was noted in 4 patients
Al Mulhim, A.N. & Kamal, H.M. (2010). Ambiguous genitalia in neonates: a 4-year prospective study in a localized area. http://www.who.int/iris/handle/10665/117845
EMHJ - Eastern Mediterranean Health Journal, 16 (2), 214-217, 2010
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Local immunity in reproductive tract tissues : proceedings of a symposium on Local Immunity in Reproductive Tract Tissues, convened by the World Health Organization Special Programme of Research, Development and Research Training in Human Reproduction and held at the National Institute of Immunology, New Delhi, India, on 26-30 November 1990 / edited by P. D. Griffin, P. M. Johnson Symposium on Local Immunity in Reproductive Tract Tissues (1990 : New Delhi, India); Griffin, P. David; Johnson, P. M; WHO Special Programme of Research, Development and Research Training in Human Reproduction (1993)