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Title: Biological activity resulting from exposure to aquatic environmental genotoxic pollutants in northern Egypt
Authors: Saad, A.A.
El Sikaily, A.M.
Kholeif, S.F.
Khalil, E.S.
Mahrous, H.S.
Al Zabedi, E.M.S.
Kassem, H.A.
Issue Date: 2010
Language: English
Abstract: We estimated pollution in Lake Edku and the Mediterranean Sea, El-Maadiya Region, with 3 aromatic amines [1-naphthylamine, 2-naphthylamine and benzidine] in the muscle tissue of fish. There were marked seasonal variations in the aromatic amine levels. We also determined oxidative stress [blood glutathione, and catalase activity] and genotoxic effects [chromosomal aberrations and urinary metabolites] in fishermen from each area. The fishermen suffered from oxidative stress and had high levels of the urinary metabolite sulfanilamide [mean [microg/mg creatinine]: Lake Edku 20.7, Mediterranean 14.5, controls 5.3]. Frequencies for total chromosomal aberrations were significantly raised in the peripheral blood lymphocytes of fishermen in both areas [frequency [per 100 metaphases]: Mediterranean 67, Lake Edku 45, controls 14]
Description: 82-88
Keywords: Water Pollutants
DNA Damage
Oxidative Stress
Subject: Environmental Pollutants
ISSN: 1020-3397
Other Identifiers:
Appears in Collections:EMRO Journal Articles (EMHJ)

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