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Title: Distinguishing between primary infection and reinfection with rubella vaccine virus by IgG avidity assay in pregnant women
Authors: Hamkar, R.
Jalilvand, S.
Abdol Baghi, M.H.
Jelyani, K.N.
Esteghamati, A.
Hagh goo, A.
Mohktari Azad, T.
Nategh, R.
Issue Date: 2009
Language: English
Abstract: During the mass measles/rubella vaccination campaign in 2003 in Iran, many pregnant women were vaccinated mistakenly or became pregnant within 1 month of vaccination. To distinguish pregnant women who were affected by rubella vaccine as primary infection from those who had rubella reinfection from the vaccine, serum samples were collected 1-3 months after the campaign from 812 pregnant women. IgG avidity assay showed that 0.3% of the women had no rubella-specific IgG response; 14.4% had low-avidity anti-rubella IgG and were therefore not immune to rubella before vaccination; 85.3% had high-avidity antirubella IgG and were regarded as cases of reinfection
Description: 94-103
Keywords: Immunoglobulin G
Immunoglobulin G
Antibody Affinity
Subject: Rubella Vaccine
ISSN: 1020-3397
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Appears in Collections:EMRO Journal Articles (EMHJ)

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