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Title: Evaluation of enzyme-linked immunosorbent assay [ELISA] in serodiagnosis of pulmonary tuberculosis
Authors: Morsi, M.G.
Youssef, R.M.
Khalil, Y.M.
Issue Date: 1997
Language: English
Abstract: A total of 45 patients with pulmonary tuberculosis and 45 healthy individuals were subjected to chest examination, radiography and ELISA tests for IgA and IgG antibodies. Sputum smear and culture were performed for all tuberculous patients. Evaluated against clinical and radiological diagnosis, ELISA's specificity exceeded 90% in detecting specific IgA and IgG antibodies. The parallel application of ELISA and microscopic examination of sputum yielded 80% sensitivity compared with clinical and radiological examination and 100% sensitivity compared with culture. ELISA alone can be used in ruling out pulmonary tuberculosis but not in diagnosing the disease. However, coupled with microscopic examination, it can be used instead of culture to provide positive diagnosis within 24 hours
Description: 480-492
Keywords: Tuberculosis, Pulmonary
Enzyme-Linked Immunosorbent Assay
Data Collection
Questionnaires
Seroepidemiologic Studies
Immunoglobulin G
Immunoglobulin A
World Health Organization
Subject: Tuberculosis, Pulmonary
URI: http://www.who.int/iris/handle/10665/117550
ISSN: 1020-3397
Other Identifiers: http://applications.emro.who.int/emhj/0303/emhj_1997_3_3_480_492.pdf
Appears in Collections:EMRO Journal Articles (EMHJ)



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