Serum level of anti-hepatitis B surface antigen 6-8 years after hepatitis B vaccination at birth
AbstractThe duration of protection after hepatitis B vaccination in children is unknown. We determined the serum level of antibody to hepatitis B surface antigen [anti-HBsAg] in 273 randomly selected 7-9-year-old schoolchildren from Zanjan City, Islamic Republic of Iran, who had been fully vaccinated against hepatitis B starting at birth. Titres </= 10 mIU/mL were considered unprotective. Just over half of the children [52%] had titres </= 10 mIU/mL with no difference between the sexes, while 81 [29.7%] had no anti-HBsAg [0 mIU/mL]. Three of the children had antibodies to hepatitis B core protein. More studies are needed to determine the necessity for or timing of booster doses
Kazemi, A., Koosha, A., Rafizadeh, B., Mousavinasab, N. & Mahram, M. (2008). Serum level of anti-hepatitis B surface antigen 6-8 years after hepatitis B vaccination at birth. http://www.who.int/iris/handle/10665/117515
EMHJ - Eastern Mediterranean Health Journal, 14 (4), 960-965, 2008
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