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Title: Evaluation of serodiagnostic tests for T.b. gambiense human African trypanosomiasis in southern Sudan
Authors: Elrayah, I.E.
Rhaman, M.A.
Karamalla, L.T.
Khalil, K.M.
Buscher, P.
Issue Date: 2007
Language: English
Abstract: A survey was conducted in a low-endemic and in a non-endemic area of Sudan to evaluate the specificity and efficiency of different serological antibody detection techniques for Trypanosoma brucei gambiense. Comparisons were made of the card agglutination test for trypanosomiasis [CATT] on diluted blood, on diluted plasma and on eluates from blood dried on filter paper, the LATEX test on diluted plasma and an ELISA on diluted plasma and filter paper. The specificities of all the serological tests were not significantly different from CATT on diluted blood [99.5%]. The specificity of CATT on diluted blood was similar [99.3%]. The highest sensitivities [100%] were observed with CATT on diluted blood and with CATT and LATEX on diluted plasma. CATT on diluted blood was more cost-efficient than the classic test, CATT on whole blood
Description: 1098-1107
Keywords: Seroepidemiologic Studies
Sensitivity and Specificity
Health Surveys
Enzyme-Linked Immunosorbent Assay
Subject: Trypanosomiasis, African
ISSN: 1020-3397
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Appears in Collections:EMRO Journal Articles (EMHJ)

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