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Title: Pattern of congenital malformations in consanguineous versus nonconsanguineous marriages in Kashan, Islamic Republic of Iran
Authors: Mosayebi, Z.
Movahedian, A.H.
Issue Date: 2007
Language: English
Abstract: This study determined the types, patterns and prevalence of congenital malformation among the offspring of consanguineous and nonconsanguineous parents. In this prospective study of 3529 neonates delivered alive during a 1-year period, 109 had congenital malformations [3.09/1000 live births]. The rate of congenital malformation was 2.0% among neonates from nonconsanguineous marriages and 7.0% from consanguineous marriages. The most common malformations were genitourinary [32.1%], musculoskeletal [22.0%] and cardiovascular [14.7%]. Of the total malformed infants, 8.3% died within the neonatal period. Male infants were at greater risk for birth malformations. A history of congenital malformation was more common in siblings of consanguineous than nonconsanguineous marriages
Description: 868-875
Keywords: Consanguinity
Sex Distribution
Prospective Studies
Subject: Congenital Abnormalities
ISSN: 1020-3397
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Appears in Collections:EMRO Journal Articles (EMHJ)

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