Letter to the Editor: diabetic nephropathy
Afifi, M. (2006). Letter to the Editor: diabetic nephropathy. http://www.who.int/iris/handle/10665/117141
EMHJ - Eastern Mediterranean Health Journal, 12 (5), 703-705, 2006
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Urinary N-acetyl-beta-D-glucosaminidase in children with diabetes as an early marker of diabetic nephropathy Abdel Shakour, S.; El Hefnawy, H.; El Yamani, M.Y.; Azmi, Y. (2002)We investigated urinary N-acetyl-beta-D-glucosaminidase [NAG] levels in children with type 1 diabetes as an early marker of tubular damage and studied its correlation with microalbuminuria and glycaemic control. The study group comprised 42 children with type 1 diabetes and 20 healthy children as control. Urinary NAG to urinary creatinine ratio, microalbuminuria, glycated haemoglobin [Hb A1c], blood urea and serum creatinine were estimated. Urinary NAG levels in the children with diabetes were significantly higher than those of controls. There ...
T-cell cytokine production and endothelial dysfunction in type 2 diabetic patients with nephropathy Kamel, L.; Morsy, A.; El Shamaa, A. (2009)This study assessed changes in serum levels of cytokines IFNgamma and IL-10 [biomarkers of inflammatory changes] and soluble biomarkers sICAM-1 and sE-selectin [biomarkers of endothelial dysfunction] in diabetic patients with and without nephropathy. IFNgamma and IL-10 were significantly elevated in patients with diabetic nephropathy [DN] and end-stage renal disease [ESRD] compared with controls and diabetic patients without DN. IFNgamma and IL-10 levels were significantly increased after haemodialysis. sICAM-1 and sE-selectin were significantly ...
Afifi, A.; El Setouhy, M.; El Sharkawy, M.; Ali, M.; Ahmed, H.; El Menshawy, O.; Masoud, W. (2004)The prevalence of diabetic nephropathy as a cause of end-stage renal disease [ESRD] in Egypt has been examined in small cross-sectional studies, with conflicting results. The need for a large-scale study prompted us to perform this 6-year multiple cross-sectional study. A sample of ESRD patients enrolled in the Egyptian renal data system was evaluated during the period 1996-2001 for the prevalence of diabetic nephropathy. Prevalence gradually increased from 8.9% in 1996, to 14.5% in 2001. The mean age of patients with diabetic nephropathy was ...