Hexadecyl- phosphorylcholine ointment for treatment of cutaneous leishmaniasis: an animal trial
AbstractA placebo- controlled trial compared 6% hexadecyl- phosphorylcholine [HePC] and 12% benzethonium chloride ointment with placebo ointment for treatment of cutaneous leishmaniasis. Cutaneous lesions were experimentally induced by inoculation with leishmania promastigotes in 60 golden hamsters. Forty  animals were treated with drug and 20 with placebo ointment applied twice daily for 15 days. After treatment, all lesions were significantly reduced in size in the treatment group compared with the placebo ointment. No parasites were detected in smears from 35/ 40 of the drug- treated lesions and no relapses occurred over 120 days of observation
Iqbal, J., Bukhari, I., Jamshid, M., Bashir, S., Masoom Yasinzai M. et al. (2006). Hexadecyl- phosphorylcholine ointment for treatment of cutaneous leishmaniasis: an animal trial. http://www.who.int/iris/handle/10665/117137
EMHJ - Eastern Mediterranean Health Journal, 12 (5), 685-689, 2006
MetadataShow full item record
Showing items related by title and MeSH subject.
Control of cutaneous leishmaniasis in Afghanistan: achievements and challenges – Lutte contre la leishmaniose cutanée en Afghanistan: progrès accomplis et défis à relever World Health Organization = Organisation mondiale de la Santé (2018-04-27)
Vectors and reservoirs of cutaneous leishmaniasis in Marvdasht district, southern Islamic Republic of Iran Rassi, Y.; Gassemi, M.M.; Javadian, E.; Rafizadeh, S.; Motazedian, H.; Vatandoost, H. (2007)An epidemiological study was made of vectors and reservoirs of cutaneous leishmaniasis in rural regions of Marvdasht, Fars province, southern Islamic Republic of Iran during 2003-04. Using live traps, 126 rodents were collected: 75.4% were Meriones libycus, 14.3% Cricetulus migratorius and 10.3% Microtus arvalis. Eight out of 95 Meriones libycus [8.4%] were found to be infected with Leishmania major, identified by nested-PCR; none of the other rodents were positive. Female sandflies were collected from indoor locations: 75% were Phlebotomus ...
Efficacy of Olyset long-lasting bednets to control transmission of cutaneous leishmaniasis in Iran Emami, M.M.; Yazdi, M.; Guillet, P. (2009)A large-scale intervention field trial of the effect of Olyset long-lasting insecticide-treated bednets on transmission of cutaneous leishmaniasis was carried out in 2 cities in the Islamic Republic of Iran from October 2003 to July 2005. We enrolled 8620 individuals in 3000 households in 6 pairs of sectors in each city. Epidemiological and entomological surveys were carried out pre- and post-intervention. In both cities a statistically significant reduction was found in the incidence of new cases in intervention sectors who received bednets ...