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Title: Measles seroepidemiology among adolescents and young adults: response to revaccination
Authors: Saffar, M.J.
Al Raza Amiri, M.
Ajami, A.
Baba Mahmoodi, F.
Khalilian, A.R.
Vahidshahi, C.
Shamsizadeh, A.
Issue Date: 2006
Language: English
Abstract: We evaluated the seroprevalence of measles antibody and response to measles re-immunization in 590 previously vaccinated adolescents and young adults; 263 were seronegative. To differentiate between primary and secondary vaccine failure, anti- measles IgM and IgG titres were assessed again 2- 4 weeks after revaccination in 144 [105 seronegative, 39 seropositive] individuals: 75 seronegative participants responded to revaccination anamnestically [P < 0.001] and developed immunity 11 also showed IgM response [probably primary vaccine failure immunity]; 38 seropositive participants, remained seroprotected without significant increase in antibody titre [P = 0.577]. Primary vaccine failure was 4.7%; secondary vaccine failure was 27.1%. After revaccination, 87.3% were seroprotected
Description: 573-581
Keywords: Measles
Measles Vaccine
Monitoring, Immunologic
Serologic Tests
Subject: Measles
ISSN: 1020-3397
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Appears in Collections:EMRO Journal Articles (EMHJ)

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