Albendazole versus metronidazole in the treatment of patients with giardiasis in the Islamic Republic of Iran
AbstractWe examined the therapeutic effects of albendazole compared to metronidazole in 120 patients with giardiasis in Hamdan. Patients were randomized to receive albendazole [400 mg, once daily for 5 days] or metronidazole [250 mg, 3 times a day for 5 days]. Demographic data of the patients, results of stool for Giardia trophozoites before and after treatment, and drug side- effects were recorded. After treatment 6 [10.0%] of the albendazole group had trophozoites compared with 14 [23.3%] of metronidazole group [P < 0.05]. Patients in the albendazole group had fewer side- effects while 43.3% of the metronidazole group experienced a metallic taste and 35.0% experienced loss of appetite. Albendazole is an easy, safe and effective treatment for giardiasis
Alizadeh, A., Ranjbar, M., Kashani, K.M., Taheri, M.M. & Bodaghi, M. (2006). Albendazole versus metronidazole in the treatment of patients with giardiasis in the Islamic Republic of Iran. http://www.who.int/iris/handle/10665/117116
EMHJ - Eastern Mediterranean Health Journal, 12 (5), 548-554, 2006
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Baqai, R.; Zuberi, S.J.; Qureshi, H.; Ahmed, W.; Hafiz, S. (2001)Albendazole and metronidazole were compared in 68 patients diagnosed positive for giardiasis. Albendazole 1200 mg, one dose was given to 24 patients, albendazole 400 mg twice a day for 3 days was given to 23 patients, and metronidazole 400 mg 3 times a day for 5 days to 21 patients. Response to therapy was monitored by clinical examination and analysis of fresh faecal samples on days 0, 3, 7 and 10. Response to the single dose of albendazole was 55%, to the divided dose of albendazole 70%, and to metronidazole 84%. The results show that albendazole, ...