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Title: Changing trends in drug resistance among typhoid salmonellae in Rawalpindi, Pakistan
Authors: Butt, T.
Ahmad, R.N.
Salman, M.
Kazmi, S.Y.
Issue Date: 2005
Language: English
Abstract: We analysed the record of blood cultures carried out at the Armed Forces Institute of Pathology, Rawalpindi between 1996 and 2003. We isolated 477 Salmonella typhi and 410 S. paratyphi A from blood of patients suffering from typhoid fever. We observed a significant shift in the distribution and antimicrobial susceptibility of typhoid salmonellae. The isolation rate of S. typhi fell significantly while S. paratyphi A is emerging as a major pathogen. Resistance to conventional antityphoid drugs in S. typhi decreased dramatically from 80% to 14%, while in S. paratyphi A resistance increased from 14% to 44%. Susceptibility to the fluoroquinolones decreased in both. No resistance to third generation cephalosporins was detected
Description: 1038-1044
Keywords: Anti-Infective Agents
Communicable Diseases, Emerging
DNA, Bacterial
Drug Utilization
Endemic Diseases
Subject: Drug Resistance, Multiple, Bacterial
ISSN: 1020-3397
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Appears in Collections:EMRO Journal Articles (EMHJ)

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