XANTHAN GUM
Overview
CAS number
11138-66-2
INS
415
Functional Class
Food Additives
EMULSIFIER
FOAMING_AGENT
STABILIZER
THICKENER
EMULSIFIER
FOAMING_AGENT
STABILIZER
THICKENER
INS matches
415
Evaluations
Evaluation year: 2016
ADI:NOT SPECIFIED
ADI:
NOT SPECIFIED
Comments:
A NOAEL of 750 mg/kg bw per day was established for xanthan gum in neonatal pigs, which are an appropriate
animal model for the assessment of the safety of the additive for infants. The margin of exposure based on this
NOAEL and the conservative estimate of xanthan gum intake of 220 mg/kg bw per day by infants (high energy
requirements for fully formula-fed infants) is 3.4. On the basis of a number of considerations, JECFA concluded that the consumption of xanthan gum in infant formula or formula for special medical
purposes intended for infants is of no safety concern at the maximum proposed use level of 1000 mg/L.
Meeting:
82
Specs Code:
R
Report:
Tox Monograph:
Specification:
Evaluation year: 1986
ADI:
NOT SPECIFIED
Meeting:
30
Specs Code:
R (1993)
Tox Monograph:
Previous Years:
1998, COMPENDIUM ADDENDUM 6/FNP 52 Add.6/165. R
1993, COMPENDIUM ADDENDUM 2/FNP 52 Add.2/135. R
1990, COMPENDIUM/1581. R
1988, FNP 38-JECFA 33/263. R,T
1986, FNP 37-JECFA 30/149. R
1985, TRS 733-JECFA 29/38, FNP 34-JECFA 29/233, FAS 6/NMRS 54A-JECFA
1998, COMPENDIUM ADDENDUM 6/FNP 52 Add.6/165. R
1993, COMPENDIUM ADDENDUM 2/FNP 52 Add.2/135. R
1990, COMPENDIUM/1581. R
1988, FNP 38-JECFA 33/263. R,T
1986, FNP 37-JECFA 30/149. R
1985, TRS 733-JECFA 29/38, FNP 34-JECFA 29/233, FAS 6/NMRS 54A-JECFA