Evaluations of the Joint FAO/WHO Expert Committee on Food Additives (JECFA)

METHYL p-HYDROXYBENZOATE

General Information

Synonyms: METHYL p-OXYBENZOATE, METHYLPARABEN
Chemical Names: METHYL p-HYDROXYBENZOATE; METHYL ESTER OF p-HYDROXYBENZOIC ACID
CAS number: 99-76-3
INS: 218
Functional Class:
  • Food Additives
    • PRESERVATIVE

Evaluations

Evaluation year: 1973
ADI: 0-10 mg/kg bw
Comments: Group ADI as the sum of the ethyl and methyl esters of p-hydroxybenzoic acid. In view of the adverse effects in male rats, propyl paraben (propyl p-hydroxybenzoate) was excluded from the group ADI for the parabens used in food (TRS 940-JECFA 67/30, 2006)
Meeting: 17
Specs Code: R (1995)
Report: NMRS 53/TRS 539-JECFA 17/17
Tox Monograph: FAS 5/NMRS 53A-JECFA 17/81
Specification: COMPENDIUM ADDENDUM 6/FNP 52 Add.6/85 (1998). R; FAO JECFA Monographs 1 vol.2/353
Previous Years: 1995, COMPENDIUM ADDENDUM 3/FNP 52 Add.3/95. R
1973, FNP 4-JECFA 17/135; COMPENDIUM/943. R
1970, NMRS 48/TRS 462-JECFA 14/24, FAS 70.41/NMRS 48C-JECFA 14/16
1965, NMRS 40/TRS 339-JECFA 9/11, FAS 67.29/NMRS 40A,B,C-JECFA 9/22, FAS 67.29/NMRS 40A,B,C-JEC