Some Thyrotropic Agents
IARC Monograph on the Carcinogenic Risks to Humans
IARC Monographs, Volume 79
ISBN-13    9789283212799 ISBN-10    9283212797
Order Number    17200079 Format    E-book collection (PDF)
Price    CHF    55.00 / US$    66.00 Developing countries:    CHF    38.50
English     2001        763   pages
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This volume evaluates carcinogenicity to humans of 19 chemicals that are carcinogenic to the thyroid follicular-cell epithelium in rodents. These included some so-called 'anti-thyroid' drugs (methimazole, methylthiouracil, propylthiou-racil and thiouracil); some sedatives (doxylamine succinate and phenobarbital); and some other drugs including the systemic antifungal antibiotic griseofulvin, the diuretic spironolactone, and the antibacterial sulfa drugs sulfamethazine and sulfamethoxazole. Other chemicals are or have been used in agriculture as pesticides (amitrole, chlordane/heptachlor, hexachlo-robenzene and toxaphene), in foods and cosmetics (kojic acid), in hair dyes (2,4-diaminoanisole) or as industrial chemicals (N,N'-diethylthiourea, ethylenethiourea and thiourea).