Research Priorities for Zoonoses and Marginalized Infections
Technical Report of the TDR Disease Reference Group on Zoonoses and Marginalized Infectious Diseases of Poverty
Technical Report Series, No 971
World Health Organization
ISBN-13    9789241209717 ISBN-10    9241209712
Order Number    11000971 Format    Paper Back
Price    CHF    40.00 / US$    48.00 Developing countries:    CHF    28.00
English     2012        130   pages
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Table of contents
EXECUTIVE SUMMARY
1. INTRODUCTION
1.1 Rationale and context
1.1 Zoonoses and the Millenium Development Goals
1.2 Challenges
1.3 Scope of the report
1.4 Group membership
1.5 Host country
1.6 Think tank members
2. METHODOLOGY AND PRIORITIZATION
2.1 Informal consultation
2.2 Selection of DRG members
2.3 First DRG meeting
2.4 Stakeholder consultations
2.5 Second DRG meeting
2.6 Priorization Process
2.7 Transformation of DRG report to TRS
3. BURDEN OF DISEASE
3.1Estimating the burden of parasitic zoonoses: approaches and challenges
3.1.1 Measures of mortality, morbidity and health-associated life years (HALYs)
3.1.2 Economic (monetary) burden of zoonotic disease
3.1.3 Case studies
3.2 Disease-specific issues and burden
3.2.1 Helminths
3.2.2 Protozoan infections
3.2.3 Bacterial infections
3.2.4 Viral infections
4. INTERVENTION-ORIENTED RESEARCH ISSUES
4.1 Community-led or community-directed interventions
4.1.1 Community-led Total Sanitation (CLTS)
4.1.2 CLTS and zoonotic diseases
4.2 The human/animal interface: "One Health" as a concept
4.3 Chemotherapy and immunization
4.3.1 Mass chemotherapy (mass-targeted, humans-animals)
4.3.2 Immunization against rabies
4.4 Vector and intermediate host control
4.5 Vaccination as a control option for zoonotic diseases
4.5.1 Animal-targeted immunization
4.5.2 Echinococcus granulosus
4.5.3 Vaccine against Taenia solium
4.5.4 Foodborne trematode vaccines
4.6 Human-targeted vaccines
4.6.1 Enteric infections
4.7 Animal reservoirs
4.8 Health education and health literacy
4.9 Development of human resources
4.10 Integrated approaches
4.11 New products and strategies
4.12 Health systems and interactions with other sectors: intersectoral dialogue
4.13 Cost?effectiveness analysis
5. DISEASE-SPECIFIC AND INTERVENTION-SPECIFIC PRIORITIES FOR RESEARCH
5.1 Disease-specific research priorities
5.1.1 Cysticercosis and taeniasis
5.1.2 Echinococcosis
5.1.3 Asian schistosomiasis
5.1.4 Foodborne trematodiases
5.1.5 Toxoplasmosis
5.1.6 Cryptosporidiosis
5.1.8 Bacterial zoonoses
5.1.9 Enteric infections
5.2 Intervention-specific research priorities
5.2.1 Community-led Total Sanitation
5.2.2 Animal/human interface
5.2.3 Epidemiological studies
5.2.4 Health education and promotion
6. CROSS-GROUP ISSUES AND PRIORITIES
6.1 Interactions with Disease and Thematic Reference Groups
6.2 Priorities for policy-makers
7. CONCLUSIONS
8. ACKOWLEDGEMENTS
9. REFERENCES
10. APPENDICES