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| Summary |
Presents the conclusions of an expert committee commissioned to evaluate the safety of residues of selected veterinary drugs used in food-producing animals, to establish acceptable daily intakes for humans, and to recommend maximum residue limits. The report has two parts. The first considers methodological issues that are specific to the safety assessment of veterinary drug residues in food. These include the potential neurotoxicity of avermectins and milbemycins, the possible impact of veterinary medicines and animal production aids on the environment and the attendant risk to consumers of multiple exposures, the effect of analytical methodology on the assignment and monitoring of maximum residue limits, and the need to standardize sampling procedures for the detection of residues at the injection site.
The second and most extensive part provides succinct summaries of the toxicological and residue data considered when evaluating each substance, identifying any potential hazards to consumer health, and allocating an acceptable daily intake and maximum residue limits. Veterinary drugs considered include six anthelminthic agents (abamectin, doramectin, moxidectin, febantel, fenbendazole and oxfendazole), four antimicrobial agents (ceftiofur, chlortetracycline, tetracycline, and oxytetracycline), and one antiprotozoal agent (diclazuril). |
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