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WHO Reporting System for Lymph Node, Spleen, and Thymus Cytopathology
ISBN: 978-92-832-4522-3
Blurb: The IAC-IARC-WHO Cytopathology Reporting Systems
The WHO Reporting System for Lymph Node, Spleen, and Thymus Cytopathology is Volume 3 of this new series of reporting systems for cytopathology, which is a joint project of the International Academy of Cytology (IAC) and the International Agency for Research on Cancer (IARC), a specialized agency of the World Health Organization (WHO). The series includes a unique synthesis of the published evidence and the practice of cytopathology, and it is linked to the WHO Classification of Tumours series, now in its 5th edition.
Cytopathologists look at tumours slightly differently than other specialists do, and there is a need for specialized reporting systems based on the key diagnostic cytopathological features of tumours, presented in standardized reports, within a hierarchical system of diagnostic categories. These categories must also be linked to diagnostic management recommendations to improve communication with clinicians and support patient care. And it is essential that these reporting systems be truly international, to serve the needs of patients worldwide in many differently medically resourced settings.
What are the key features of this first edition of the series?
These volumes are an essential tool for standardizing diagnostic cytopathology practice worldwide and will serve as a vehicle for the translation of cytopathology research into practice. The key diagnostic cytopathological features listed for each tumour type under the diagnostic categories represent the first international consensus and are described in precise, uniform language. These diagnostic criteria are underpinned by available evidence that has been evaluated and debated by experts in the field. Lesion-specific sections include discussion of the differential diagnosis of the lesions’ cytopathological features that can be used worldwide, especially in low-resource settings, followed by a discussion of the current best-practice application of ancillary testing on cytopathology material.
This volume
- Prepared by about 40 authors and editors
- Contributors from around the world, reflecting an international expertise
- Hundreds of high-quality images
- More than 1000 references
Online version
- The content of this new, innovative, and comprehensive cytopathology reporting series is also available in a convenient digital format, at https://tumourclassification.iarc.who.int

WHO Classification of Endocrine and Neuroendocrine Tumours, 5th edition
ISBN: 978-92-832-4524-7
Blurb:
The WHO Classification of Tumours
Endocrine and Neuroendocrine Tumours is Volume 10 in the 5th edition of the WHO series on the classification of human tumours. This series (also known as the WHO Blue Books) is regarded as the gold standard for the diagnosis of tumours and comprises a unique synthesis of histopathological diagnosis with digital and molecular pathology. These authoritative and concise reference books provide indispensable international standards for anyone involved in the care of patients with cancer or in cancer research, underpinning individual patient treatment as well as research into all aspects of cancer causation, prevention, therapy, and education.
What’s new in this edition?
The 5th edition, guided by the WHO Classification of Tumours Editorial Board, establishes a single coherent cancer classification presented across a collection of individual volumes organized on the basis of anatomical site (digestive system, breast, soft tissue and bone, etc.) and structured in a systematic manner, with each tumour type listed within a taxonomic classification: site, category, family (class), type, and subtype. In each volume, the entities are now listed from benign to malignant and are described under an updated set of headings, including histopathology, diagnostic molecular pathology, staging, and easy-to-read essential and desirable diagnostic criteria.
- Pathologists
- Endocrinologists
- Medical oncologists
- Surgical oncologists
- Radiation oncologists
- Radiologists
- Nuclear medicine specialists
- Molecular pathologists
- Geneticists
- Immunologists
- Cancer researchers
- Epidemiologists
- General practitioners
- Oncology nurses
- Cancer registrars
This volume
- Prepared by 175 authors and editors
- Contributors from around the world
- More than 1100 high-quality images
- More than 5100 references
WHO Classification of Tumours Online
All volumes of the series, with additional figures, whole slide images, and more, can also be accessed online: https://tumourclassification.iarc.who.int

IARC Scientific Publication No. 171
Statistical Methods in Cancer Research Volume V: Bias Assessment in Case–Control and Cohort Studies for Hazard Identification
ISBN: 978-92-832-2229-3
Blurb: Observational epidemiology is used to identify the causes of cancer and other chronic diseases, to determine the effectiveness of interventions, and to understand reasons for differences in disease rates over time or across locations. Reviewers of observational epidemiology studies must judge whether a causal interpretation is supported, including whether chance, bias, and confounding can be reasonably ruled out.
This Scientific Publication was supported by a scientific workshop on epidemiological bias assessment in hazard identification, convened by IARC and funded in part by the United States National Cancer Institute. It summarizes the wide range of practical methods that can be used by a reader or reviewer of a publication to assess the potential impact of confounding, information bias (including differential and non-differential exposure and outcome misclassification), or selection bias on the results of an epidemiological study. The methods presented include indirect approaches, for example negative control outcomes or exposures and proxies, and other approaches, such as sensitivity analyses.
The methods are presented in a way that is accessible to epidemiologists and other research workers who do not have extensive statistical training, as well as to statisticians who do not have extensive epidemiological training. The concepts are illustrated with numerous practical examples, taken from cancer epidemiology, that recur throughout the chapters, as well as links to online code or spreadsheets.
The book also outlines the process for integrating these bias assessments into the evidence synthesis. The process that is outlined uses the wide array of methods described in the book to consider all informative studies.
Finally, it is hoped that this book will encourage authors to apply a wider range of direct and indirect bias assessments in their primary research publications. Broader adoption of these analyses will enhance the quality of the original papers and further improve the interpretation of the evidence in subsequent reviews.

WHO Classification of Paediatric Tumours, 5th edition. Part A

WHO Classification of Paediatric Tumours, 5th edition. Part B
WHO Classifiation of Tumours . 5th Edition: Paediatric Tumours
ISBN: 978-92-832-4510-0
Paediatric Tumours is Volume 7 in the 5th edition of the WHO series on the classification of human tumours. This series (also known as the WHO Blue Books) is regarded as the gold standard for the diagnosis of tumours and comprises a unique synthesis of histopathological diagnosis with digital and molecular pathology. These authoritative and concise reference books provide indispensable international standards for anyone involved in the care of patients with cancer or in cancer research, underpinning individual patient treatment as well as research into all aspects of cancer causation, prevention, therapy, and education.
What’s new in this edition?
The 5th edition, guided by the WHO Classification of Tumours Editorial Board, will establish a single coherent cancer classification presented across a collection of individual volumes organized on the basis of anatomical site (digestive system, breast, soft tissue and bone, etc.) and structured in a systematic manner, with each tumour type listed within a taxonomic classification: site, category, family (class), type, and subtype. In each volume, the entities are now listed from benign to malignant and are described under an updated set of headings, including histopathology, diagnostic molecular pathology, staging, and easy-to-read essential and desirable diagnostic criteria.
Who should read this book?
- Pathologists
- Oncologists
- Radiologists
- Surgeons
- Oncology nurses
- Cancer researchers
- Epidemiologists
- Cancer registrars
This double volume
- Prepared by 413 authors and editors
- Contributors from around the world
- More than 2400 high-quality images
- More than 7800 references
WHO Classification of Tumours Online
The content of this renowned classification series is now also available in a convenient digital format: https://tumourclassification.iarc.who.int
Part A
- Introduction to paediatric tumour
- Haematolymphoid disorders
- CNS tumours
- Peripheral neuroblastic tumours
- Eye tumours
- Soft tissue and bone tumours
Part B
- Germ cell tumours
- Renal and male genital tumours
- Female genital tumours
- Breast tumours
- Digestive system tumours
- Endocrine tumours
- Head and neck tumours
- Thoracic tumours
- Skin tumours
- Genetic tumour syndromes
Number of pages:
- PART A : 664
- PART B: 564

Bulletin of the World Health Organization