Some Drugs and Herbal Medicines
IARC Monographs on the Evaluation of Carcinogenic Risks to Humans
IARC Monographs, Volume 108
ISBN-13    9789283201465 ISBN-10    9283201469
Order Number    17200108
Price    CHF    55.00 / US$    66.00 Developing countries:    CHF    38.50
English     2016        434   pages
This volume of the IARC Monographs provides an assessment of the carcinogenicity of 14 drugs and herbal products.

The IARC Monographs Working Group relied mainly on epidemiological studies to evaluate the carcinogenic hazard to humans exposed to the drugs digoxin (widely prescribed for the treatment of chronic heart failure), pioglitazone (used for the treatment of type 2 diabetes mellitus), and hydrochlorothiazide (used to treat hypertension).

Other agents evaluated included the drugs primidone, sulfasalazine, pentosan polysulfate sodium, and triamterene, and five herbal products (or their components): Aloe vera whole leaf extract, goldenseal root powder, Ginkgo biloba leaf extract, kava extract, and pulegone. In view of the limited agent-specific information available from epidemiological studies, assessments of these agents relied mainly on carcinogenicity bioassays to reach conclusions as to the carcinogenic hazard to exposed humans..