Vaccines: Preventing Disease and Protecting Health
PAHO Scientific Publications, No 596
PAHO
ISBN-13    9789275115961 ISBN-10    9275115966
Order Number    16100596
Price    CHF    93.00 / US$    111.60 Developing countries:    CHF    65.10
English     2004        412   pages
Summary
***This book has been recognized for "excellence and its unique contribution to scholarly publishing in the medical science" by the Association of American Publishers

This book examines the various ways vaccines have played a role in improving the health of the world's populations. The successful efforts to fight disease with vaccines, including the eradication of polio from the Americas, and the potential contribution of new measles vaccine formulations to reducing measles mortality worldwide are discussed. Challenges posed in using vaccines to cope with emerging and re-emerging diseases, such as HIV/AIDS and bioterrorism, are highlighted. The authors provide analyses of innovative efforts underway to test the efficacy of vaccines against diseases such as meningococcal infection in Africa, Haemophilus influenza type b, varicella, and hepatitis A, and look at efforts to develop a new generation of vaccines against cholera and typhoid, shigella, and Helicobacter pylori. The advances in influenza vaccine development and Hepatitis C are also presented.
The book includes sections on the quest for vaccines against tuberculosis, HIV/AIDS, dengue, malaria, and hookworm. New concepts for vaccine development, adjuvants and delivery systems such as maternal immunization, DNA vaccines, and oral vaccines derived from transgenic plants are also discussed. Sections of the book deal as well with the use of vaccines against potential bioterrorism attacks, with a particular emphasis on smallpox and anthrax. Regulatory and safety issues related to vaccines are also presented from the various perspectives of the public sector, the pharmaceutical industry, and the vaccine consumer.
The final chapter highlights the ongoing challenges of vaccine development, disease prevention, internal and external financing and sustainability of immunization programs, and the impact of health sector reform on these issues.